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Introduction and Overview

Substance Information Evidence-Based Strategies for Preventin...

Who is this document for? This document is to assist community leaders, local and regional organizers, non-profit groups, law enforcement, public health, and members of the public in understanding and navigating effective strategies to prevent opioid overdose...

Guiding Principles

Substance Information Evidence-Based Strategies for Preventin...

Below are four overarching principles, lessons gleaned from previous public health emergencies, such as the HIV/AIDS crisis in the 1980s and 1990s. These principles serve as a guide for the design and implementation of effective overdose prevention strategies....

Targeted Naloxone Distribution

Substance Information Evidence-Based Strategies for Preventin...

Naloxone is an opioid antagonist that can quickly and safely reverse the potentially fatal effects of an opioid overdose. Targeted distribution programs seek to train and equip individuals who are most likely to encounter or witness an overdose—especially peop...

Medication-Assisted Treatment (MAT)

Substance Information Evidence-Based Strategies for Preventin...

MAT is a proven pharmacological treatment for opioid use disorder. The backbone of this treatment is FDA approved medications. Agonist drugs, methadone and buprenorphine, activate opioid receptors in the brain, preventing painful opioid withdrawal symptoms wit...

Academic Detailing

Substance Information Evidence-Based Strategies for Preventin...

“Detailing” is a structured educational strategy developed by commercial manufacturers of medical and pharmaceutical technologies to market these products to prescribers and pharmacists. “Academic detailing” consists of structured visits to healthcare provider...

Eliminating Prior-Authorization Requirements for Medications for Opioid Use Disorder

Substance Information Evidence-Based Strategies for Preventin...

In this scenario, health insurance providers cover the cost of MAT as a standard benefit and all requirements that a physician contact the insurance provider for approval prior to writing the prescription (a process called “prior authorization”) are removed. W...

Screening for Fentanyl in Routine Clinical Toxicology Testing

Substance Information Evidence-Based Strategies for Preventin...

The standard panel of substances included in routine clinical drug screens (carried out in hospitals, clinics, treatment centers, etc.) should include screening for fentanyl exposure, particularly in jurisdictions where fentanyl is known to be prevalent in the...

911 Good Samaritan Laws

Substance Information Evidence-Based Strategies for Preventin...

The term "911 Good Samaritan Law" refers to local or state legislation that may provide overdose victims and/or overdose bystanders with limited immunity from drug-related criminal charges and other criminal or judicial consequences that may otherwise result f...

Naloxone Distribution in Treatment Centers and Criminal Justice Settings

Substance Information Evidence-Based Strategies for Preventin...

Naloxone distribution programs in criminal justice and treatment facilities (both inpatient  and outpatient) target individuals who are about to be released from supervision and/or cease treatment to receive overdose response training and naloxone kits prior t...

MAT in Criminal Justice Settings and Upon Release

Substance Information Evidence-Based Strategies for Preventin...

In this intervention, MAT should be available as a standard of care for incarcerated individuals with opioid use disorder. Those receiving MAT when they enter a criminal justice setting may continue receiving this treatment, and those who are not on treatment ...

Syringe Services Programs

Substance Information Evidence-Based Strategies for Preventin...

Sometimes called "needle exchange" or "syringe exchange," syringe programs provide access to clean sterile equipment used for the preparation and consumption of drugs as well as tools for the prevention and reversal of opioid overdose, such as naloxone trainin...

Initiating Buprenorphine-based MAT in Emergency Departments

Substance Information Evidence-Based Strategies for Preventin...

Patients receiving care in emergency departments who have untreated opioid use disorder are referred to a provider for long-term buprenorphine-based MAT. This referral is accompanied by initial doses of buprenorphine or a short-term prescription that can be fi...

Preventing an Opioid Overdose: Know the Signs. Save a Life. (CDC)

Substance Information

Opioid Overdose Basics Prescription opioids (like hydrocodone, oxycodone, and morphine) and illicit opioids (like heroin and illegally made fentanyl) are powerful drugs that have a risk of a potentially fatal overdose. Anyone who uses opioids can experience a...

Using Data to Better Understand Substance Use Disorder and Opioid Use Disorder

Substance Information Rural Community Action Guide

Using Data to Better Understand Substance Use Disorder and Opioid Use Disorder By NORC Walsh Center For Rural Health Analysis More than 70,000 people in the United States died from a drug overdose in 2017, and approximatelytwo-thirds of those deaths involv...

Impact of Addiction on A Rural Community

Substance Information Rural Community Action Guide

Impact of Addiction on A Rural Community Partner Insight and Recommended Action Steps Drug addiction in rural America is more than just a health issue. This is a matter of rural prosperity. A 2017 report by the White House Council of Economic Advisors esti...

Managing The Push And Pull On Fiscal Resources During The Opioid Crisis

Substance Information Rural Community Action Guide

Managing The Push And Pull On Fiscal Resources During The Opioid Crisis By National Association of Counties Challenging Fiscal Factors in Rural Counties Rural counties in America are making progress on the ground level in the fight against opioid addictio...

Workforce Development: Increasing Opportunities For Employment During The Opioid Crisis

Substance Information Rural Community Action Guide

Workforce Development: Increasing Opportunities For Employment During The Opioid Crisis By National Association of Development Organizations Rural Businesses Face Unique Challenges Rural businesses typically face unique challenges to their success, such a...

Action Steps to Bridge the Transportation Gap

Substance Information Rural Community Action Guide

Transportation is a significant challenge for persons with SUD who lack access to public transit or other modes of transportation. Rural communities can implement programs that provide transportation to people on demand, for any reason. Communities that are in...

Taking Action To Address Substance Use Disorder In The Farming Community

Substance Information Rural Community Action Guide

Taking Action To Address Substance Use Disorder In The Farming Community By American Farm Bureau Federation / National Farmers Union Opioid Impacts On Farming Community A survey by Morning Consult commissioned in 2017 by the American Farm Bureau Federatio...

Information About Opioids (NIH)

Substance Information

Opioids are a class of drugs that include synthetic opioids such as fentanyl; pain relievers available legally by prescription, such as oxycodone (OxyContin®), hydrocodone (Vicodin®), codeine, morphine; the illegal drug heroin; and many others. Use of opioids...